Discovery of a Novel Nephroprotective Drug Leveraging a Customized Photoacoustic Imaging Nanoprobe

RESEARCH HIGHLIGHT

研究亮点

构建可逆响应过氧亚硝酸根与谷胱甘肽氧化还原失衡的 TB@MP 光声成像纳米探针，用于肾缺血再灌注损伤早期识别和天然肾保护活性成分筛选，并发现角鲨烯可通过缓解氧化应激、炎症反应及 AKT/NF-κB 信号异常发挥保护作用。

完整引文

Wangning Zhang#, Ming Yang#, Xinhao Zhu, Jiaxin Zhang, Zhenheng Jiao, Bo Chen, Xianchuang Zheng*, Jiangwei Tian*, Xunfang Ding*. Discovery of a Novel Nephroprotective Drug Leveraging a Customized Photoacoustic Imaging Nanoprobe. Advanced Functional Materials, 2026, e22425.